High resolution crystal structures of SF1 enzymes in complex with DNA and various nucleotide ... and hydrolysis of nucleoside triphosphates, helicases move along nucleic acid filaments and ...

To date, there are no approved commercially available vaccines, and anti-HSV-1 drugs such as specific or non-specific nucleotide (nucleoside) analogs and helicase-primase inhibitors have become the ...

The tryptic peptides were acidified to pH 3 with 10% formic acid and desalted using hand-packed stage tips of C18 resin. The peptides were eluted with 80% acetonitrile and 0.1% formic acid and were ...

Celery, a key vegetable in the Apiaceae family, is widely valued for its nutrition and medicinal uses. It is commonly categorized into three varieties: A. graveolens var. dulce (common celery ...

The NTP and dNTP hydrolysis reactions were performed in a reaction mixture consisting of 50 mM Tris–HCl (pH 8.0), 250 mM KCl, 2 mM MgCl 2, 2 mM DTT, 1 μM DDX1, and 1 mM nucleotide or ... different ...

Autonomous nanocomputing agents made of nucleic acids and proteins are an appealing idea, and two decades of research has shown that the engineered agents act under real physical and biochemical ...

Facile Modifications at the C4 Position of Pyrimidine Nucleosides via In Situ Amide Activation with 1H-Benzotriazol-1-yloxy-tris(dimethyl-amino)phosphonium Hexafluorophosphate.