Clazosentan – an intravenously-administered endothelin A receptor antagonist – is designed to prevent cerebral vasospasm in aSAH patients, a sudden narrowing of blood vessels that can occur in ...

BACKGROUND: The etiology of cerebral ischemic accidents in young ... A search for possible causes of vasospasm was unsuccessful. After treatment with calcium antagonists the patient was free ...

altered cerebral and ocular circulation, vasospasm, and direct damage to the optic nerve head, he said. Tin Aung OSA-induced hyper-hypoxia is likely a mechanism that glaucomatous optic neuropathy ...

Introduction After aneurysmal subarachnoid hemorrhage (SAH), both proximal and distal cerebral vasospasm can contribute to the development of delayed cerebral ischemia. Intra-arterial (IA) ...

Purpose: Cerebral vasospasm (CVS) is a common complication that occurs after neurosurgical clipping of intracranial aneurysms in patients with aSAH. This complication can lead to clinical ...

DCI often occurs in the settings of cerebral vasospasm and is, therefore, thought to be largely driven by local hypoperfusion, 7 although alternative mechanisms likely contribute. 8 The vasospasm and ...

Conversely, factors such as advanced age, vasospasm, brain swelling, calcification, and the feasibility of a safe endovascular approach may steer decisions away from clipping. Large aneurysms with ...

We performed a matched pair analysis to evaluate the effect of heparin on cerebral vasospasm (CVS), cerebral infarction (CI), and outcome. Results The rate of severe CVS was significantly reduced in ...

Rapidly becoming standard of care in Japan with neurosurgeons for prevention of cerebral vasospasm in patients with aneurysmal subarachnoid haemorrhage (aSAH) Market share increased from 57% in 2023 ...

Scientists have developed a lipid nanoparticle system capable of delivering messenger RNA (mRNA) to the brain via intravenous injection, a challenge that has long been limited by the protective ...

Neuralink's brain implant chip, 'the Link,' connects human brains to computers, aiding those with paralysis in movement control. Neuralink’s brain implant chip is a bold step toward merging ...