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ribosome-occupancy-plot
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Frontiers1mon
Challenges in characterization of transcriptomes of extracellular vesicles and non-vesicular extracellular RNA carriers
2006). However, careful analysis of sEV pellets in iodixanol gradients revealed the presence of a distinct non-vesicular fraction (NVF) enriched with metabolic enzymes (GAPDH, PKM, ENO1), cytoplasmic ...
Frontiers1mon
Ribosomal RNA Pseudouridylation: Will Newly Available Methods Finally Define the Contribution of This Modification to Human Ribosome Plasticity?
Despite its clear role in enabling proper ribosome function and its involvement in human pathology, the mechanism underlying the contribution of rRNA pseudouridylation in the development of human ...
eLife8y
The ribosomal protein Asc1/RACK1 is required for efficient translation of short mRNAs
Thompson et al. have now explored the role of Asc1 in yeast cells by measuring translation in the absence of Asc1 using a technique called ribosome footprint profiling. This analysis revealed that ...
eLife9y
Many lncRNAs, 5’UTRs, and pseudogenes are translated and some are likely to express functional proteins
Using a new bioinformatic method to analyze ribosome profiling data, we show that 40% of lncRNAs and pseudogene RNAs expressed in human cells are translated. In addition, ~35% of mRNA coding genes are ...