These medications work by acting like the nucleotide cytosine and incorporating ... The most common HDAC inhibitors include phenylbutyric acid, SAHA, depsipeptide, and valproic acid (Egger et ...

The Nucleic Acids Institute is dedicated to understanding the chemical and biological basis for nucleic acid function, and to developing new and powerful nucleic acids based therapeutic and ...

Notably, IDEA learns the interaction matrix between each amino acid and nucleotide, allowing for direct interpretation of the “molecular grammar” governing the binding specificities of DNA binding ...

Together with new in vitro HBV infection systems, based on the identification of the bile acid transporter sodium taurocholate cotransporting polypeptide as an HBV entry receptor, this offers novel ...