Target identification is the process of identifying the direct molecular target – for example protein or nucleic acid – of a small ... highly selective kinase inhibitors remains challenging.

Among the various derivatives of phenoxyacetic acids, 2,4-D (salts and esters) and MCPA (salts) are widely used as herbicides ...

The most common HDAC inhibitors include phenylbutyric acid, SAHA, depsipeptide, and valproic acid (Egger et al., 2004). Caution in using epigenetic therapy is necessary because epigenetic ...

Along with researchers in the Faculty of Health Sciences and the Faculty of Science, Western projects received a total of $17 ...

Although gut microbiota and lipid metabolites have been suggested to be closely associated with type 2 diabetes mellitus (T2DM), the interactions between gut microbiota, ...

Can we fix errors in our genetic blueprint that lead to debilitating disorders like Huntington's disease?How can we better support newcomers to Canada ...

An MTF2-containing subcomplex of Polycomb Repressive Complex 2 promotes cell cycle progression through repression of D-type cyclin expression in certain cellular contexts.

In 2004, a research group at Peking University First Hospital discovered a mutation in the gene coding for a sodium-channel ...

Newco Akribion Therapeutics GmbH has raised €8 million (US$8.3 million) in a seed round to develop a new and potent class of RNA-targeted CRISPR nucleases, which, rather than cleaving specific nucleic ...

The Nucleic Acids Institute is dedicated to understanding the chemical and biological basis for nucleic acid function, and to developing new and powerful nucleic acids based therapeutic and ...

Yerba mate contains antioxidants, caffeine, and other nutrients. Some research suggests it may enhance physical performance, boost energy levels, and support weight management. Yerba mate is a ...

To get the GTA Online Acid Lab up and running, speak to Mutt near the truck and pay the GTA$750,000 fee to install the lab equipment – though this is free if you subscribe to GTA+.