Cody Gakpo could return to the Liverpool starting XI against Newcastle United while Arne Slot also faces a Dominik Szoboszlai dilemma when making his team selection.
Cody Gakpo, Conor Bradley, Joe Gomez latest news and return dates - The champions-elect are boasting an almost fully fit squad
Slot confirmed Joe Gomez and Cody Gakpo will both be unavailable for Wednesday's game: "Cody is the closest to coming back but Joe will take quite some time. He is going to be out for a number of weeks because of a hamstring injury."
After a 2-1 win over Wolverhampton Wanderers on Sunday, the Reds rebuilt their seven-point buffer at the top of the Premier League table. A win at Villa Park would put them 10 points clear and crank up the pressure on chasers Arsenal.
Curtis Jones will return from a one-game ban served in the 2-1 win over Wolverhampton Wanderers, although Cody Gakpo remains a doubt owing to the knock he sustained in last week's Merseyside derby.