Plants and fungi can use conserved RNA interference machinery to regulate each other’s gene expression—and scientists think they can make use of this phenomenon to create a new generation of ...

The secondary structure of the mRNA target site has ... Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells. Nature 411, 494–498 (2001).

An RNA interference (RNAi ... Instead, the startup’s drugs employ what she described as a divalent structure in which two small-interfering RNA (siRNA) duplexes are joined by a linker.

With small molecules, which make up an estimated 90% of approved medicines 1, each new medicine requires in-depth knowledge of the structure ... an approach called RNA interference (RNAi) are ...