The sugar-phosphate backbone forms the structural framework of nucleic acids ... an ester bond with the free hydroxyl on the 3' carbon of the next nucleotide. These bonds are called phosphodiester ...

One area of research has explored the influence of sequence variation on the RNA cleavage activity of artificial ribonucleases based on peptide nucleic acids ... Phosphodiester linkage: A covalent ...

Nucleic acids are complex biological molecules that store and transmit genetic information in all living organisms. They are essential for the survival and reproduction of life on Earth. The two main ...